Lara. In monkeys killed at the end of exposure (13 or 52 weeks), Sr was taken up in a dose-dependent manner into compact and cancellous bone, with a higher content in new bone than in old bone. The researchers hypothesized that strontium like calcium may activate a calcium-sensing receptor on breast cells that increases the expression of estrogen receptors, and thus have an estrogen-like effect. I also discuss bone building exercises and diet. I dont know what type of exercise regimen you follow, but in both exercises and your daily activities, it is very important NOT to do movements that flex your spine forward into a big C curve. Strontium (Citrate) is an alkali earth metal, very similar in structure to Calcium, and has a similar effect in the body. The drug form has been shown to greatly increase risk for venous thromboembolism (blood clot formation in the deep veins very dangerous) and DRESS syndrome (if you develop a rash while taking strontium ranelate, see your doctor IMMEDIATELY; DRESS syndrome is very serious, requires quick treatment and possibly hospitalization). Now I am barely osteopenic and expect my next DXA will show I am fully in the healthy normal range. 196 And a recent meta-analysis of 12 well-controlled trials comparing hydroxyapatite to calcium carbonate to prevent bone loss found Inflammation, when chronic, promotes destruction of tissue in the joints (thus the osteoarthritis already noted) and activates osteoclasts excessively, increasing the rate of bone turnover. Id appreciate your response to these concerns. I came off and just took calcium supplements. A creatinine clearance rate of 90 or greater indicates normal healthy kidney function. I do plan on continuing the algae cal plus but question if I need 4 capsules each day or if I can cut the dosage. I do have one suggestion for you you might get in touch with Cancer Treatment Centers of America. PAHs are known to be capable of provoking autoimmune reactions, including DRESS, TENS and more. 99% of Strontium is located in the teeth and bones where it promotes replication of preosteoblastic cells, which maintain bone health. ), then check the references he provides (probably none) to ensure the papers he is basing his claims upon actually say what he is using them to assert. I remember when my mother was dying from hip fracture + congestive heart failure along with my 23 year old cat, who we were giving fluids several times a day because of her kidney failure I was so stressed out and sad that I lost TONS of hair. Pregnancy or breastfeeding: Don't take without approval from your healthcare provider. So when we take strontium if our diet is not providing adequate magnesium, we may need a bit more magnesium to maintain the optimal 2:1 balance between calcium and magnesium this is the provided in AlgaeCal Plus. Keep asking questions! I recommend (and use myself) the MK-7 form of K2 for a number of reasons too many to go into in any meaningful way here. 2012 Jan;112:212-7. doi: 10.1016/j.envres.2011.11.005. Our kidneys eliminate strontium far more quickly than calcium: three times as much strontium is lost in urine compared to calcium. I have hyponatremia. Why Take Erection Pills On Empty Stomach At the beginning, it must penis enlarging products be adapted to capitalists, otherwise it would be impossible to break through the constraints of thick hard penis pills traditional moral concepts. Strontium ranelate slows down the cells that break down bone. Moreover, too much fiber and fructose in fruits can also make slow down your digestive system if eaten on an empty stomach. This has caused me to seriously wonder if Im trading one problem for a more serious one down the road. And 340 mg/d is the amount of Strontium Boost I will continue to take to maintain that condition. This is a pristine environment, and AlgaeCal does everything possible to keep it that way. Once bone health is restored, a maintenance dose of 340 mg per day should be both safe and sufficient. These are the 4 and 16alpha -OH compounds derived from estrogen, which are pro-inflammatory. I hope this information is helpful for you. Very glad to hear you are doing many of the things I noted that are essential for healthy bones. 2001 Sep;69(3):121-9. As you work your way through Your Bones, I hope you will use it to figure out how much your diet is providing for you of the nutrients essential for building healthy bones and what and how much you will need to get from supplements. The bottom line here: To err on the side of safety, I would not recommend the use of strontium citrate in young, premenopausal women. Until about 8 years ago, it was assumed that everyone could convert beta-carotene to vitamin A, but we now know that, in fact, the vast majority of us are not able to make this conversion because our genetic inheritance includes slow or completely ineffective versions of the key enzymes responsible for this job. That is troubling to me as do not want to end up with hyper-calcium. The aim of the strontium ranelate (SR) for treatment of osteoporosis (STRATOS) trial was to investigate the efficacy and safety of different doses of SR, a novel agent in the treatment of postmenopausal osteoporosis. If this happens on an empty stomach with no food present to disperse the highly concentrated vitamins and minerals, the result can be nausea. That goes for both the density and the tensile quality of your bones. As a result, a treatment with Strontium should not induce any alteration of bone mineral.. Fat-soluble vitamin supplements will be harder to absorb on an empty stomach, and they can also lead to an upset stomach. Easily exchangeable in bone mineral, Sr was slightly linked to crystals by ionic substitution (generally 1 calcium ion substituted by 1 Sr ion in each unit cell). It has not. I take Strontium Bone Maker every day along with my New Chapter Bone Strength Take Care Calcium supplement. I suggest you take a careful look at the labels on the housecleaning and body care products you are using and eliminate any that may be suspect for 4-5 days. If you would like to read up about hormone testing and the 24 Hour Urine, I wrote an article for physicians about all this that is available at Longevity Medicine Review heres a link: Osteoporosis treatment should not only prevent the loss of bone tissue, not interfere with apatite and avoid bone mineral changes at the crystal level, but should also increase the mechanical resistance of bone and thus protect the skeleton against new fractures. I would be interested to learn of any further research on Lactoferrin and its positive effects on bone building. Once you are tested and find out where your imbalances are (and this will be clearly shown on the 24 Hour Urine test for all the estrogens, progesterone, DHEA, testosterone, your adrenal hormones and more), you can restore balance. We have found in the more than 6,000 patients we have now tested in a health promotion project we have been involved in up in Calgary that virtually everyone needs at least 2,000 IU per day, many need 5,000 IU per day or even more.) Another action you can take that can dramatically lower your inflammation and help protect your joints and bones is to take 2 tablespoons daily of Triple Power. If you are using something else, please do check that your diet and supplements combined are not giving you more than 1,200 mg of calcium, 600 mg of magnesium and 680 mg of strontium citrate each day. Yogurt is a great option here if dairy products agree with you, look for whole milk, organic yogurt from pastured cows, which will also provide vitamin K2 as well as calcium for you. In addition to reading your blog I also read a blog from an osteoporosis site. Many cellular processes do not happen effectively in an acidic environment, and furthermore, an acidic pH (called metabolic acidosis) over activates osteoclasts and promotes bone loss. 2014 Oct 7;4(10):e005787. I was diagnosed with osteoporosis last month & I started taking AgaeCal & Strontium Boost this month. https://www.progressivenutritional.com/products/multivitamin-for-women-50. Most people get somewhere around 400 mg/day or more of calcium from their normal diet (e.g., milk, yogurt, cheese, leafy greens, soymilks and yogurts, etc., also enriched with calcium in Your Bones, I provide a full listing of the foods rich in calcium, how much is in a typical serving, so you can figure out what YOU are getting). If you have osteopenia or osteoporosis you should take two capsules daily on an empty stomach. Hope this helps. A member of the American Medical Writers Association for more than 25 years, Lara publishes and reviews articles covering breaking research on bone health in Integrative Medicine: A Clinicians Journal. The other night I contacted the manufacturer of my strontium and inquired as to if the supplement was better absorbed on an empty stomach or with food. So, Im writing you directly with a brief summary of some of the relevant information provided in my update on strontium, which I hope will allay your concerns. Heartburn, stomach pain, or diarrhea; back, muscle, or joint pain; a headache, and flu-like symptoms are the most common side effects. What do you recommend for me age 74 with fine bonesand osteoporosis with the above BMD results? In terms of this small an amount of strontium having beneficial effects on bone as well as teeth I have not seen any research indicating this low a dose would be beneficial in bone. Yes, your email arrived, although I dont see it posted here in the Comments section yet, so I will copy in and respond to your questions here. So many thanks, Dave and Susan. I have just found out that a dear friend has a rare bone cancer Osteasarcoom. Consequently, they have a very large interface with extracellular fluids, and numerous interactions between ions from the extracellular fluid and ions constituting apatite crystals are thus possible. (We should take more calcium than strontium in order for both to be effective.) So how can the real amount, if any, of increase in strength and quality of bone be known or determined? I already had osteoporosis before I started on the drug and this drug is known to cause bone loss so Im happy to have found algae cal plus, but do you have thoughts about whether the strontium is necessary or safe under these circumstances? Our study suggests that LIPUS may be a new method of treatment without surgery for metastatic bone tumors. In conclusion, the different studies performed on bone samples from monkeys and humans treated with various doses of SR showed that Sr was heterogeneously distributed between new and old bone but in a dose-dependent manner without alteration of the crystal characteristics and the degree of mineralization of bone tissue, even after long-term administration of often high doses of SR (the highest therapeutic dose used in humans is 4-fold lower than the lowest experimental dose administered to monkeys). I have already purchased Drs Best Strontium Bone Maker (Strontium Citrate), and wonder if, in your opinion, Strontium Boost is a better product. Sorry to hear youre experiencing nausea not fun! Conventionally grown vegetables have been shown to contain far less of many minerals, so if you are not eating organic, all bets are off here. The bottom line is: Strontium citrate improves healthy bone mineralization and resistance to fracture. K. Niu, R. Ahola, H. Guo et al., Effect of office-based brief high-impact exercise on bone mineral density in healthy premenopausal women: the Sendai Bone Health Concept Study, Journal of Bone and Mineral Metabolism, vol. I may drop down to 1/4 the dosage though. I agree with your assumptions on thyroid and iodinegreat article by the way, I hope others reading these posts will check it outI felt the same way, but I wanted to ask you because I could see that you had already done an extensive amount of research and willing to answer peoples questions/concerns. Based on your previous response to me I should probably add to my K2 amount. If not you can find this information on the internet, but be sure you check to see how much is being said to be a serving. In additional to calcium-containing foods, foods that contain alginate (found in kelp) lower strontium absorption, and so do certain medications, including quinolone antibiotics, and medications that contain aluminum hydroxide or magnesium hydroxide. Thank you for magnificent info I was in search of this info for I also e-mailed Meunier and asked if his cited study (or any he knew of) suggested 170 mg to be more effective than 680 mgas the above people are citing him as demonstrating that. OK to your questions: I do not know what your multivitamin contains. The effects of strontium ranelate on the risk of i do notyetstill egfr in 80s. Subjects were 160 postmenopausal women, mean age 73 years, with a hip BMD value of more than 2 standard deviations below the reference value, so clearly well into the osteopenic / osteoporotic range. You can wear a hat and put sunscreen on your face to prevent wrinkling and age spots, but leave at least your arms and legs bare and sunbathe. Hi Lara, Note that the COMB study was conducted by Dr. GenUIs (not Genius)I have contacted his office regarding the type of exercise that was used by patients in the study and was surprised to learn that he recommends jumping, running, or jogging (exercises that are typically contraindicated for osteoporotic patients), working up to 300 repetitions. Oncol Rep. 2012 Aug;28(2):481-6. doi: 10.3892/or.2012.1816. I do Pilates daily myself and also lift weights and take a dance type aerobic class called Zumba a couple of times each week. Be well! Hi Laura, You recommended calcium citrate, malate, gluconate, aspartate, or hydroxyapatite over calcium carbonate in calcium supplements, yet calcium carbonate appears to be the major form of calcium found in the algae used in Algaecal. But if you prefer, you can take your Triple Power with food as it doesn't have any interactions. These statements have not been evaluated by the Food and Drug Administration. You were correct. Please advise soonest, if it is okay for me to take the Algae Plus without the strontium as I am suffering of thrombocytopenia as well. Strontium distribution and interactions with bone mineral in monkey iliac bone after strontium salt (S12911) administration. What are your thoughts on the amount of magnesium to calcium/strontium? Maybe its just me. Stay gloriously well, Lara. We use Key Pharmacy here in Washington state, and we have ordered nebulized NAC for patients with COPD as far away as FLA. Looking forward to your response. Hi Lara, I have a hard time with taking the strontium at night. A comparison of adverse event and fracture efficacy data for strontium ranelate in regulatory documents and the publication record. I also take bioidentical estrogen. However, osteomalacia is also frequently seen in end-stage kidney failure patients who are not yet on dialysis and who have normal bone strontium levels. As long as the juice or tea does not contain calcium. Dr. Grout does offer BHRT. For those of us taking strontium citrate I personally find this article to be somewhat disturbing. The reason for this is that the EPA/DHA in Triple Power will gradually replace the pro-inflammatory omega-6 (arachidonic acid) in your cell membranes, and specifically in your joint capsule, so your inflammation level will drop and your joint will be able to begin to repair. Thanks for sharing. Any issues? You just want to take strontium at a time when you are not also consuming calcium since the two minerals compete for absorption (and calcium always wins, so you will get little benefit from your strontium if you take it when also consuming calcium). I took a look at the study this is one short term (90 day) rat study done back in 1977. This means that youll reach the recommended 1200mg of calcium each day, all through food sources! I sent the following reply to one of them to share there: I found the discussion and have been looking and looking and looking for any research showing strontium citrate is toxic. A previously developed in vivo X-ray fluorescence (IVXRF) I-125 based system was used to measure bone strontium levels non-invasively in an osteoporotic female volunteer. I thought this might be in one of the two papers you kindly provided links to, but I could not find anything re thyroid in these, and I have seen nothing suggesting this in any of the papers on natural forms of strontium that I have read. Thanks for looking and for your input. Phosphate, as well as calcium, significantly lowers strontium absorption. Hello, I am 69 years old and my dexa scan says I have osteoporosis. You can always try taking strontium again after a months break to see if your symptoms recur.. Many commonly prescribed drugs cause hyperprolactinemia. 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